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: During the energy investment phase: Glucose + 2 ATP = ?

A) Pyruvate + 2 NADH
B) Pyruvate + 4 ATP
C) Pyruvate + 2 ADP
D) Pyruvate + 2 ATP

1 Answer

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Final answer:

The energy investment phase of glycolysis consumes two ATPs to phosphorylate glucose. Following this phase, the net products of glycolysis are 2 pyruvate, 2 ATP (net gain), and 2 NADH, from one molecule of glucose.

Step-by-step explanation:

During the energy investment phase of glycolysis, the input is glucose and 2 ATP, and this phase consumes ATP rather than producing it. Specifically, two ATP molecules are used to phosphorylate glucose.

As the process continues, glycolysis proceeds to generate a total of four ATP molecules, two NADH molecules, and two pyruvate molecules. However, since two ATPs are consumed at the beginning, the net gain is two ATPs and two NADH molecules, with the generation of two pyruvate molecules.

Therefore, the correct answer to the question 'During the energy investment phase: Glucose + 2 ATP =' is not direct because it is a multi-step process. However, the overall outcome of glycolysis can be summarized as Glucose + 2 ATP + 2 NAD+ + 4 ADP + 2 Pi → 2 Pyruvate + 4 ATP + 2 NADH + 2H+, with a net yield of 2 Pyruvate, 4 ATP (but net 2 because 2 were invested), and 2 NADH.

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