Final answer:
The relationship between total load and the velocity of shortening of a myocyte is inversely related; as one increases, the other decreases. This is a central concept in the physiology of muscle contraction, particularly regarding the length-tension relationship.
Step-by-step explanation:
The relationship between the total load and the velocity of shortening during contraction of the myocyte has been studied and is best described as an inverse relationship. As the load on a muscle increases, the velocity at which the myocyte can shorten during contraction decreases. This concept is relevant to the length-tension relationship in muscle physiology, in which the optimal overlap of myosin and actin filaments within the sarcomere allows for maximum contractile force. However, when a myocyte contracts against a high load, the rate of contraction, or velocity of shortening, will be slower than when contracting against a lighter load.