Final answer:
In teaching about wound healing by secondary intention, it should be noted that granulation tissue formation is the key process, as the wound heals from the bottom-up and is not sutured or stapled closed.
Step-by-step explanation:
The correct information to include when teaching about wound healing by secondary intention is that granulation tissue forms to fill in the wound area during this healing process. Secondary intention healing occurs in cases where the wound edges cannot be brought together, such as with large or irregular wounds. Instead of being sutured or stapled, the wound is left open to heal from the bottom-up. As healing progresses, fibroblasts lay down collagen fibers and form granulation tissue, which eventually contracts and pulls the wound edges together. Although this process is slower, it allows for the filling of gaps when tissue loss is significant.
Option D is the most accurate: D. Granulation tissue forms to fill in the wound area during secondary intention healing. Primary union, or primary intention healing, refers to wound edges that are close together and may be sutured or stapled, facilitating faster and tidier healing, which is not the case with secondary intention.