Final answer:
The question relates to high-level aminoglycoside resistance which is associated with Enterococcus species, part of the ESKAPE pathogens group. These bacteria can become resistant to multiple antimicrobials and are a significant cause of nosocomial infections. The correct option is c.
Step-by-step explanation:
The question asks about high-level aminoglycoside resistance, which is a topic relating to the study of antibiotic resistance in bacteria. Aminoglycosides, such as Gentamicin, Streptomycin, and Tobramycin, are antibiotics used to treat bacterial infections, and resistance to these drugs can be a major clinical concern.
The resistance mechanisms used by bacteria such as efflux pumps, which can export multiple antimicrobial drugs out of the cell, are often nonspecific to a particular class of antimicrobials.
Enterococcus species, specifically Enterococcus faecium, have developed high-level aminoglycoside resistance and are part of the ESKAPE pathogens, which have become resistant to multiple antimicrobials.
Enterococcus, being a part of the normal intestinal microbiota, can persist in individuals and becomes concerning when it acquires multidrug resistance, making infections difficult to treat. This group of bacteria is known for causing a number of nosocomial or hospital-acquired infections. The correct option is c.