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In the Kleihaur-Betke apt test, fetal RBCs will be ________________ pH change & maternal RBCs will be ___________________ to pH change

A) Resistant, Sensitive
B) Sensitive, Resistant
C) Alkaline, Acidic
D) Acidic, Alkaline

User Ziwei
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Final answer:

In the Kleihaur-Betke test, fetal RBCs are resistant to pH change, while maternal RBCs are sensitive. The correct option is A) Resistant, Sensitive. This test is significant in conditions like erythroblastosis fetalis.

Step-by-step explanation:

Kleihaur-Betke Test Explanation

In the Kleihaur-Betke apt test, designed to detect fetal red blood cells (RBCs) within the maternal circulation, fetal RBCs will be resistant to pH change, while maternal RBCs will be sensitive to pH change. The correct answer to the student's question is A) Resistant, Sensitive. This test is used in cases such as erythroblastosis fetalis, where maternal anti-Rh antibodies destroy fetal Rh+ red blood cells. This hemolytic condition can lead to severe issues such as anemia, agglutination, and possibly fetal demise if left untreated.

User DWR
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