Question

IP presents to the pharmacy with a prescription for phenelzine (Nardil) to treat her depression. She wants to refill an old prescription on file for her migraine headaches. She cannot recall the name of the migraine medication but she knows that it is a "triptan." Which medication can she safely take with phenelzine?

A. Imitrex
B. Maxalt
C. Relpax
D. Zomig
E. Treximet

Answer 1

None of the medications listed (Imitrex, Maxalt, Relpax, Zomig, or Treximet) can be safely taken with phenelzine due to the risk of serotonin syndrome, a serious and potentially life-threatening condition.

Step-by-step explanation:

The use of phenelzine, a monoamine oxidase inhibitor (MAOI), for the treatment of depression must be carefully managed due to potential interactions with other medications. Phenelzine can lead to serious side effects if combined with drugs that also affect the serotonergic system, such as triptans used for migraine headaches. All the medications listed — Imitrex (sumatriptan), Maxalt (rizatriptan), Relpax (eletriptan), Zomig (zolmitriptan), and Treximet (sumatriptan/naproxen) — are triptans. None of these should be taken with phenelzine due to the risk of a serious interaction known as serotonin syndrome. Therefore, the correct answer is that none of the listed medications can be safely taken with phenelzine.

Hence, the answer is not provided among options.