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Why are CORVETs and HOPS different? Why are they similar?

A. Different subunit composition; Both involved in Golgi transport
B. Different functions; Both involved in vesicle fusion
C. Different initiation signals; Both function as motor proteins
D. Different coat proteins; Both function as vesicle tethers

User Soshika
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1 Answer

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Final answer:

B. Different functions; Both involved in vesicle fusion

CORVETs and HOPS are multicellular protein complexes with different functions related to vesicle fusion within the cell. While CORVETs are associated with early endosomes, HOPS complexes function with late endosomes and lysosomes. Both share a common aspect, which is their involvement in the process of vesicle fusion.

Step-by-step explanation:

The CORVET and HOPS complexes are distinct tethering complexes involved in different stages of vesicle fusion within the cell.

CORVETs (Complexes Associated with Tethering Containing Helical Rods) are primarily associated with early endosome functions, while HOPS (Homotypic Fusion and Protein Sorting) complexes are involved with late endosome and lysosome functions.

Both these complexes, however, are similar in that they have a common role in facilitating vesicle fusion, but they differ in their subunit composition and the specific stages of endosomal trafficking they are involved in.

Therefore, for the question asked, the correct answer would be B. Different functions; Both involved in vesicle fusion. CORVETs and HOPS both assist in the fusion of vesicles, but they have different functional roles within the cell.

User Raniz
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