Question

RD has significant nausea during her migraine headaches and cannot tolerate swallowing any pills. She vomits them right back up. Which of the following formulations might provide benefit? Select ALL that apply.

A. Maxalt MLT
B. Zembrace SymTouch
C. Onzetra Xsail
D. Zomig ZMT
E. Amerge

Answer 1

Maxalt MLT, Zembrace SymTouch, Onzetra Xsail, and Zomig ZMT might provide benefit for a patient with migraine headaches who suffers from significant nausea, as these do not require swallowing pills.

Step-by-step explanation:

The student is inquiring about alternative migraine headache treatment options for someone who is experiencing significant nausea and is unable to tolerate oral pills due to vomiting. The formulations that might provide benefit without needing to swallow pills include:

• Maxalt MLT (Rizatriptan benzoate), which is a melt-in-your-mouth tablet that disintegrates on the tongue.
• Zembrace SymTouch, which is a subcutaneous injection providing sumatriptan.
• Onzetra Xsail, which is sumatriptan powder administered nasally using a breath-powered delivery system.
• Zomig ZMT (Zolmitriptan), another orally disintegrating tablet similar to Maxalt MLT.

However, Amerge (Naratriptan), while it is a migraine medication, is not suitable in this case since it is only available in a standard oral tablet form which may not be tolerated by someone who has severe nausea.