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How does energy/strain change with relation to the SNAREs during vesicle fusion?

A. Energy is released; Energy is absorbed
B. Energy is absorbed; Energy is released
C. Energy remains constant
D. No energy involved

User Antonpuz
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1 Answer

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Final answer:

During vesicle fusion, SNARE proteins release energy as they move from a strained state during the docking of the vesicle to a target membrane, to a relaxed state upon completion of fusion.

Step-by-step explanation:

During vesicle fusion, SNARE proteins play a crucial role in facilitating the process. SNAREs facilitate the docking and merging of the vesicle and target membranes.

The correct answer is A. Energy is released; energy is absorbed. Initially, the SNARE complexes are in a strained state; during the fusion, they twist tighter together, which helps pull the membranes into close proximity. Upon completing the fusion, the strain energy is released when the complex attains a more relaxed state.

The energetics of this process can be related to an exothermic reaction where energy is released due to the product (the fusion of the vesicle and target membrane facilitated by SNAREs) being of lower energy compared to the reactants (separate vesicle and target membrane with unpaired SNAREs).

On the other hand, the initial energy is absorbed to assemble and prime the SNARE complexes and charge the system so that it can proceed with the fusion process.

User Nesan Mano
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