Final Answer:
The addition of new sugars during glycosylation primarily occurs in the Trans-Golgi network, where final modifications take place. Therefore, the correct answer is option C) Trans-Golgi.
Step-by-step explanation:
Glycosylation is a post-translational modification process where sugar molecules are added to proteins or lipids to form glycoconjugates. In the Golgi apparatus, glycosylation occurs in different stages: cis-Golgi, medial-Golgi, and trans-Golgi. However, it is specifically in the trans-Golgi network (TGN) where the final modifications, including addition of new sugars, take place.
The cis-Golgi receives vesicles containing proteins from the endoplasmic reticulum, and as these proteins progress through the Golgi cisternae (cis to medial to trans), various sugar moieties are added or modified.
The trans-Golgi network is crucial for the sorting and packaging of proteins into vesicles that are directed to their final cellular destinations. So, the addition of new sugars during glycosylation primarily occurs in the trans-Golgi, making option C the correct choice.
Therefore, the correct answer is option C) Trans-Golgi.