Question

What is the difference in roles between ATP-dependent and ATP-independent chaperones?

A) ATP-dependent chaperones assist in protein degradation
B) ATP-independent chaperones are involved in translation
C) ATP-dependent chaperones require ATP for folding assistance
D) ATP-independent chaperones bind to ATP during the folding process

Answer 1

ATP-dependent chaperones require ATP for folding assistance, while ATP-independent chaperones do not. Examples of ATP-dependent chaperones include Hsp70 and Hsp90, while ATP-independent chaperones include small heat shock proteins (sHSPs) such as α-crystallin.

Step-by-step explanation:

The difference in roles between ATP-dependent and ATP-independent chaperones is as follows:

ATP-dependent chaperones require ATP for folding assistance. They use ATP to power their conformational changes and assist proteins in folding correctly. Examples of ATP-dependent chaperones include Hsp70 and Hsp90. On the other hand, ATP-independent chaperones do not require ATP for their folding assistance. These chaperones assist proteins in folding without using ATP. Examples of ATP-independent chaperones include small heat shock proteins (sHSPs) such as α-crystallin.