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3 major metabolites produced by gut microbiota

A) Short-chain fatty acids (SCFAs), bile acids, vitamins
B) Ammonia, hydrogen peroxide, lipopolysaccharides
C) Histamine, serotonin, melatonin
D) Urea, acetylcholine, prostaglandins

User Paul Leigh
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1 Answer

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Final answer:

The three major metabolites produced by gut microbiota are short-chain fatty acids (SCFAs), bile acids, and vitamins.

Step-by-step explanation:

The correct answer is: A) Short-chain fatty acids (SCFAs), bile acids, vitamins. Gut microbiota, composed of trillions of microorganisms residing in the digestive tract, play a crucial role in metabolic processes. Among the numerous metabolites they produce, the three major categories include:

1. Short-chain fatty acids (SCFAs): These are byproducts of the fermentation of dietary fibers by gut bacteria. SCFAs, such as acetate, propionate, and butyrate, serve as an energy source for the host and exert various health benefits, including supporting the integrity of the intestinal lining.

2. Bile Acids: Gut bacteria modify primary bile acids produced by the liver, transforming them into secondary bile acids. Bile acids are essential for fat digestion and absorption.

3. Vitamins: Gut microbiota contribute to the synthesis of certain vitamins, including B vitamins (e.g., B12, folate) and vitamin K, which play key roles in various physiological processes.

These metabolites highlight the intricate relationship between the gut microbiota and host metabolism, influencing health and disease outcomes. Options B and C represent other metabolites produced by gut bacteria but are not the major ones typically associated with their beneficial effects. Option D includes urea, which is produced by the host's liver, not the gut microbiota, making option A the most accurate choice.

User Saurabh Kumar
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