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Which of the following cell junctions is involved with anchoring the extracellular matrix to the cell?

I. Focal adhesions
II. Desmosomes
III. Hemidesmosomes
IV. Gap junctions
A) I and II
B) II and III
C) III and IV
D) I and IV

1 Answer

2 votes

Final answer:

The cell junctions involved with anchoring the extracellular matrix to the cell are focal adhesions and hemidesmosomes. The correct answer to the question is I. Focal adhesions (not provided in references but generally known) and III. Hemidesmosomes, so the answer is B) II and III.

Step-by-step explanation:

The question is asking which cell junctions are involved in anchoring the extracellular matrix to the cell. The cell junctions that perform this function are focal adhesions and hemidesmosomes. Focal adhesions are not explicitly described in the provided references, but they are known for linking the extracellular matrix to the cytoskeleton via integrins. Hemidesmosomes resemble half a desmosome and include adhesion proteins called integrins, as opposed to cadherins in desmosomes, that anchor cells to the extracellular matrix, such as the basal lamina. Desmosomes, on the other hand, bind cells to each other rather than to the matrix. Meanwhile, gap junctions facilitate intercellular communication and are not involved in anchoring to the matrix. Therefore, the correct answer to which cell junctions are involved with anchoring the extracellular matrix to the cell is I. Focal adhesions and III. Hemidesmosomes, so the option that includes both is B) II and III.

User Tommaso Taruffi
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