Final answer:
The marker added to lysosomal hydrolases in the cis Golgi network is A) Mannose-6-phosphate, which signals their transport to the lysosomes. Disorders in glycoprotein modification often involve the Golgi apparatus.
Step-by-step explanation:
The marker added to lysosomal hydrolases in the cis Golgi network is Mannose-6-phosphate (A).
This marker functions as a signal, tagging the hydrolases to ensure their proper sorting and transport to the lysosomes.
Congenital disorders of glycosylation, which affect the proper modification of glycoproteins, primarily involve the Golgi apparatus.
As it is the organelle responsible for the final steps in glycoprotein synthesis, including tagging proteins with various sugars and sorting them to their intended destinations within the cell.