Final answer:
Yes, RNA can base pair with itself through intramolecular base pairing, forming a stable three-dimensional structure crucial to its function.
Step-by-step explanation:
Can RNA base pair with itself? The answer is yes, RNA can pair with itself. This process is known as intramolecular base pairing and is crucial to the RNA's function. Even though RNA is typically single-stranded, it can fold upon itself to form a three-dimensional structure. This structure is stabilized by complementary base pairs, where nucleotides within the same RNA molecule pair with each other based on base-pairing rules similar to those in DNA, except that adenine pairs with uracil instead of thymine.