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Which set of reagents could accomplish the following chemical transformation?

A. 1. Mg; 2. HBr
B. 1. CH3MgBr; 2. H3O+
C. 1. MgBr2; 2. H3O+
D. 1. PBr3; 2. Mg
E. 1. Br2; 2. Mg"

1 Answer

5 votes

Final answer:

Option B, which includes CH3MgBr and H3O+, is the most likely to achieve a chemical transformation that involves the use of a Grignard reagent and an acidic work-up.

Step-by-step explanation:

The question asks which set of reagents could accomplish a specific chemical transformation. The correct set of reagents must be capable of adding a bromine (Br) atom to a molecule, a process often achieved through the formation of a Grignard reagent followed by the addition of a source of bromine.

For instance, adding elemental magnesium (Mg) to a bromoalkane can generate a Grignard reagent which can then react further.

Considering the provided options and the typical reactions these reagents undergo, option B with CH3MgBr and H3O+ as the second step would be the most likely to achieve a transformation involving the addition of a carbon group via a Grignard reagent to some substrate, followed by an acidic work-up to give the final product.

The Mg in CH3MgBr would be a part of the Grignard reagent initially, and the H3O+ would serve to protonate and thereby finalize the formation of the new molecule.

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