Final answer:
The CYP enzyme that breaks down benzodiazepines is CYP3A4, and researchers use specific inhibitors and CYP substrate probes in baculosomes to study the metabolism of drugs like gabapentine enacarbil in vitro.
Step-by-step explanation:
The specific CYP enzyme responsible for breaking down benzodiazepines is CYP3A4. When identifying the CYP enzymes involved in the metabolism of drug compounds like gabapentine enacarbil, researchers often use specific inhibitors of each isoform to assess their role. In research settings, the influence of gabapentine enacarbil on the metabolism of CYP substrate probes is analyzed using baculosomes in a 96-well format, which allows for the assessment of in vitro inhibition of CYP isoenzymes.