Final answer:
In Twelve Angry Men, Juror 8 is the protagonist who is opposed by antagonists Juror 3, Juror 10, and Juror 4, as they challenge his pursuit of justice with their own biases and perceptions.
Step-by-step explanation:
In the play Twelve Angry Men, Juror 8 is unequivocally the protagonist, facing resistance as he seeks to ensure a fair deliberation in a murder trial. The antagonists in this drama are primarily those jurors who pose the greatest opposition to Juror 8's point of view, hindering his quest for justice.
One such juror is Juror 3, whose personal biases cloud his judgment, leading him to doggedly argue for a guilty verdict regardless of reasonable doubt. Juror 10 is another antagonist, whose bigotry and prejudice interfere with a fair assessment of the case. Also, Juror 4 stands as an antagonist through his reliance on logic and facts, which, while seemingly reasonable, initially prevents him from considering the possibility of innocence. These characters, through their confrontations with Juror 8, embody the thematic conflicts of the play: justice versus injustice and the search for truth in the face of prejudice.