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Which of the following is not a mechanism by which plasmids ensure their inheritance and maintenance during cell division?

a. high-copy-number plasmids
b. low-copy-number plasmids
c. carrying antibiotic resistance genes
d. carrying partitioning system genes, parc, parm, and parr
e. carrying self-preservation genes, known as addiction modules

1 Answer

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Final answer:

While the question suggests one option is not a mechanism for plasmid inheritance in cell division, all listed options (high-copy-number plasmids, low-copy-number plasmids, antibiotic resistance genes, partitioning system genes, and addiction modules) are recognized mechanisms.

Step-by-step explanation:

The question asks which of the following is not a mechanism by which plasmids ensure their inheritance and maintenance during cell division:

  • a. High-copy-number plasmids
  • b. Low-copy-number plasmids
  • c. Carrying antibiotic resistance genes
  • d. Carrying partitioning system genes, parC, parM, and parR
  • e. Carrying self-preservation genes, known as addiction modules

All options listed, except for choice (d), are established methods by which plasmids maintain themselves in bacterial populations.

High-copy-number plasmids and low-copy-number plasmids provide mechanisms for plasmids to replicate independently of the host's chromosomal DNA, ensuring they are present in daughter cells post cell division.

The presence of antibiotic resistance genes makes the plasmids advantageous for bacterial survival in environments with antibiotics, thereby promoting their maintenance and spread within a bacterial population through natural selection.

Furthermore, addiction modules ensure the survival of plasmids by killing the host cell if the plasmid is lost, making them essential for the plasmid's inheritance.

However, the presence of partitioning system genes, such as parC, parM, and parR, is a mechanism that plasmids utilize to ensure proper segregation during cell division, and is not the correct answer.

These systems are involved in the accurate distribution of plasmids to daughter cells during binary fission. Therefore, there seems to be an error in the question as all options listed are recognized mechanisms.

If this is a genuine mistake in the question, it should be addressed so the student can be provided with accurate information.

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