Final answer:
The most soluble substance in water would be a small hydrophilic molecule, such as methanol (CH3OH). Nonpolar molecules, like octane (C8H18), are hydrophobic and do not dissolve well in water.
Step-by-step explanation:
Water is considered a polar solvent, and substances that are polar or ionic will dissolve in it. The most soluble substance in water would be a small hydrophilic molecule. Examples of small hydrophilic molecules include methanol (CH3OH). On the other hand, nonpolar molecules, such as octane (C8H18), are hydrophobic and do not dissolve well in water.