Final answer:
3rd generation antipsychotics commonly cause weight gain, metabolic disturbances, extrapyramidal symptoms, cardiovascular effects, and endocrine disturbances as side effects.
Step-by-step explanation:
The major side effects of 3rd generation antipsychotics can include weight gain and metabolic problems, extrapyramidal symptoms (EPS), cardiovascular effects, and endocrine disturbances. These medications, used to treat symptoms of schizophrenia and other mental health conditions, work by antagonizing dopamine receptors, which can lead to a variety of side effects. Weight gain and metabolic issues such as diabetes are quite common.
EPS are less common with 3rd generation antipsychotics compared to earlier generations but can include tremors, rigidity, and bradykinesia. Cardiovascular effects might encompass an increased heart rate, hypertension, and a higher chance of heart attacks. Additionally, endocrine disturbances can lead to hormonal imbalances that manifest in various ways, including sexual dysfunction or menstrual irregularities.