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Which compounds are macroergic and donate Pi?

User Mbursill
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Final answer:

Macroergic compounds such as ATP, NAD+, FAD, and CoA are central to metabolic pathways by donating Pi, transferring electrons, and acetyl groups. ATP, in particular, is known for energy transfer and hydrolysis of pyrophosphate to Pi.

Step-by-step explanation:

Compounds that are macroergic and have the ability to donate a phosphate group, often referred to as inorganic phosphate or Pi, are crucial in the metabolic pathways of organisms. Among these, adenosine triphosphate (ATP) is the most significant. ATP functions as a temporary storage molecule for energy and readily donates a phosphate group during biochemical reactions, crucial for the transfer of energy.

Nicotinamide adenine dinucleotide (NAD+) and flavin adenine dinucleotide (FAD) are also important as they are involved in electron transfer during biological oxidation-reduction reactions. Additionally, coenzyme A (CoA) is vital for the transfer of acetyl groups. The hydrolysis of pyrophosphate (PPi) to 2 Pi is an important example of how these compounds contribute to their respective metabolic functions, which makes the reaction irreversible thus driving metabolic processes forward.

User Magnus Jensen
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