Question

What is the MOA of Ezetinibe (Zetia)- inhibitor of NPC1L1 Ezetinibe/simvastatin (with statin)?

Answer 1

Ezetimibe, also known as Zetia, is an inhibitor of the NPC1L1 protein. By inhibiting NPC1L1, Ezetimibe blocks the absorption of dietary cholesterol, resulting in reduced levels of cholesterol in the body.

Step-by-step explanation:

Ezetimibe, also known as Zetia, is an inhibitor of the NPC1L1 protein. NPC1L1 is a protein found in the small intestine that plays a key role in the absorption of cholesterol from the diet. By inhibiting NPC1L1, Ezetimibe blocks the absorption of dietary cholesterol, resulting in reduced levels of cholesterol in the body.