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Which drugs are bile acid-binding resins or sequestrants?

User Ray Oei
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Final answer:

Bile acid-binding resins or sequestrants are medications like cholestyramine, colestipol, and colesevelam, which help lower blood cholesterol levels by preventing the reabsorption of bile acids in the intestines.

Step-by-step explanation:

The question pertains to a class of lipid-lowering agents known as bile acid-binding resins or sequestrants. These drugs help to lower cholesterol levels in the blood by binding to bile acids in the intestine, thus preventing them from being reabsorbed. This process ultimately leads to the liver converting more cholesterol into bile acids to replace those that are lost, which in turn lowers the level of cholesterol circulating in the bloodstream. Examples of bile acid sequestrants include cholestyramine, colestipol, and colesevelam.

These drugs are often used in conjunction with other lipid-lowering agents such as statins or niacin to enhance the cholesterol-lowering effect. However, when used in combination, the patient must be carefully monitored due to potential side effects such as an increased risk of myopathy or rhabdomyolysis.

User M Soegtrop
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