Final answer:
Conditions that are contraindications for Tramadol include severe respiratory depression, hypersensitivity to the drug, opioid addiction, acute intoxication with alcohol or other CNS depressants, a high risk of seizures, concurrent use of MAOIs, and severe hepatic or renal impairment.
Step-by-step explanation:
Several conditions serve as contraindications for administering Tramadol, an opioid analgesic. It is important not to use Tramadol in patients with a history of severe respiratory depression or hypersensitivity to the drug. Also, those with a current or past history of opioid addiction should avoid this medication. Instances of acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids, or psychotropic drugs are contra-indicative as well. The medication should be used with caution in individuals with a risk of or current seizures, as Tramadol may lower the seizure threshold and increase the risk of seizures. Also, certain medications like monoamine oxidase inhibitors (MAOIs) should not be taken with Tramadol because of the risk of serious side effects, including serotonin syndrome. Patients with severe hepatic or renal impairment should also not take Tramadol, as it may lead to increased levels of the drug in the body, further amplifying the risk of side effects.