Final answer:
Lymphedema is the accumulation of interstitial fluid in tissues caused by a blockage in the lymphatic vessels, often resulting in swelling and potential medical complications.
Step-by-step explanation:
The term for the accumulation of interstitial fluid in tissue due to blocked lymphatic vessels is called lymphedema. This condition occurs when the lymphatic system is unable to properly drain excess fluid, often leading to swelling. For example, 20 liters of plasma is released into the interstitial space of tissues each day, of which 17 liters are reabsorbed by blood vessels, and the remaining three liters are supposed to be drained by the lymphatic system. If lymphatic vessels are obstructed, this drainage is impaired, causing protein-rich interstitial fluid to accumulate in the affected tissues.
Conditions such as cancer, injury, or infections can result in the damage to or blockage of lymphatic capillaries, preventing them from carrying excess interstitial fluid and white blood cells from the tissue spaces back into the bloodstream. This leads to systemic edema, which can cause significant discomfort and potential medical complications.