Question

What is the first clinical sign of Landau-Kleffner syndrome?

1) Language regression
2) Seizures
3) Hyperactivity
4) Sleep disturbances

Answer 1

The first clinical sign of Landau-Kleffner syndrome is language regression, where children experience a loss of previously acquired language skills. Hence, option (1) is correct.

Step-by-step explanation:

The first clinical sign of Landau-Kleffner syndrome is generally language regression. While seizures and other symptoms like irritability and sleep disturbances can also be present, they may not be the initial indicators of this neurological disorder.

Language regression in Landau-Kleffner syndrome can be particularly troubling as it affects the ability to understand or use spoken language, which is known as aphasia. This loss or deterioration of language skills in a previously normal child is often the first and most prominent feature that parents and physicians notice.

Therefore, the correct answer is option (1) Landau-Kleffner syndrome.