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The risk of transient neurological symptoms is most likely to occur with which local anaesthetic?

1) Chloroprociane
2) Lignocaine
3) Bupivacaine
4) Prilocaine

1 Answer

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Final answer:

The local anesthetic most likely to cause transient neurological symptoms is chloroprocaine. It works by blocking sodium channels on nerves, preventing sensation, and sometimes motor function. Although these effects are temporary, chloroprocaine has a higher incidence of such symptoms.

Step-by-step explanation:

The risk of transient neurological symptoms is most likely to occur with chloroprocaine. Of the options provided, chloroprocaine has been associated with these transient symptoms following spinal anesthesia.

Local anesthetics like chloroprocaine, lidocaine, bupivacaine, and prilocaine work by blocking voltage-gated sodium channels on neuronal membranes. This inhibition prevents the propagation of action potentials along the nerves, leading to a reversible loss of sensation and potential motor function in the targeted area. When applied to a specific site, these anesthetics can cause numbness by stopping the initiation and transmission of sensory impulses. They act on any part of the nervous system and on every type of nerve fiber.

Chloroprocaine, specifically, has been linked to a higher incidence of transient neurological symptoms, such as pain or discomfort in the lower back and buttocks, although these effects are rare and generally resolve without treatment. Other local anesthetics like lidocaine are considered very effective due to their ability to create a reversible block of nerve conduction without causing permanent structural damage to nerve fibers or cells.

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