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Regarding pralidoxime, which of the following statements is correct?

1) It regenerates acetylcholine receptors
2) It regenerates acetylcholine
3) It regenerates succinylcholine
4) It regenerates acetylcholinesterase

User Kemia
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Final answer:

Pralidoxime regenerates acetylcholinesterase after poisoning by nerve agents, reactivating the enzyme so it can continue to break down acetylcholine.

Step-by-step explanation:

Regarding pralidoxime, the correct statement is that it regenerates acetylcholinesterase. Pralidoxime chloride (2-PAMCI) is a medication used to treat poisoning by nerve agents, where it reactivates acetylcholinesterase that has been inactivated by an organophosphate nerve agent. This process involves scavenging the phosphoryl group from the enzyme, thus counteracting the effects of the nerve agent and allowing acetylcholinesterase to break down acetylcholine in the synaptic cleft, which is critical for proper neuronal transmission.

User Michael Thessel
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