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Regarding diazepam, which of the following statements is CORRECT?

1) It is metabolised to oxazepam
2) It is an enzyme inducer
3) It should not be used in convulsions of unknown origin
4) It has a half life of 4 hours

User Adyusuf
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Final answer:

The correct statement regarding diazepam is that it is metabolized to oxazepam, it has a long half-life, and is utilized as an anticonvulsant for managing seizures to improve prognosis and prevent brain damage. It is not an enzyme inducer and whether it should be used in convulsions of unknown origin depends on individual clinical assessment.

Step-by-step explanation:

The correct statement regarding diazepam is that it is metabolized to oxazepam. Diazepam is a medication that belongs to a class known as benzodiazepines, which includes various other drugs such as Alprazolam (Xanax), Bromazepam, Chlordiazepoxide (Librium), Clonazepam (Klonopin), Lorazepam (Ativan), Temazepam, and Triazolam. Specifically, diazepam undergoes metabolism by the liver, where it is converted into several active metabolites, including oxazepam. Contrary to the statement regarding its half-life, diazepam has a long half-life, typically ranging from 20 to 50 hours, far longer than 4 hours.

Diazepam is widely used in the medical field as an anticonvulsant and is administered to manage seizures. It is essential in improving the long-term prognosis for seizure patients and reducing the risk of brain damage. Diazepam's administration is generally not self-managed and is indicated for use in actively seizing patients. Regarding its role in convulsions of unknown origin, clinical judgment is vital; it may or may not be contraindicated based on a patient's specific circumstances and after ruling out certain contraindications.

It is crucial to understand that diazepam is not an enzyme inducer but rather can have inhibitory effects on certain enzymes involved in drug metabolism. A healthcare professional must always be consulted for detailed information on drug interactions and specific patient-related factors before using diazepam.

User AlteredConcept
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