Final answer:
During an inflammatory response, increase in phagocytes, swelling, and an increase in blood flow are typical, while pale cold skin is the least likely to occur.
Step-by-step explanation:
During an inflammatory response to injury, the region of the injury typically becomes red, warm, and swollen due to an increase in blood flow and the presence of inflammatory chemicals like histamine. This increased perfusion brings phagocytes such as neutrophils and macrophages to the site of injury to neutralize pathogens and clear debris. Consequently, swelling is caused by the leakage of fluid from the blood vessels into the surrounding tissue.
Of the options provided, the least likely occurrence in the region of the injury during an inflammatory response is pale cold skin. This is because the inflammatory process typically leads to redness and warmth due to vasodilation, increased perfusion, and the subsequent arrival of immune cells to the damaged area.