Final answer:
Familial Benign Pemphigus is also known as Hailey-Hailey Disease, a genetic disorder causing recurrent blisters and lesions on the skin. It results from ATP2C1 gene mutations and is managed symptomatically.
Step-by-step explanation:
Familial Benign Pemphigus is also known as Hailey-Hailey Disease. This is not to be confused with Pseudoxanthoma elasticum, Systemic lupus erythematosus, or other genetic disorders such as Ehlers-Danlos syndrome or Hereditary hemorrhagic telangiectasia. Hailey-Hailey Disease is a rare genetic condition characterized by recurrent blisters and lesions primarily in the body's folds, such as the armpits and groin.
The disease is caused by mutations in the ATP2C1 gene, leading to malfunctions in calcium pumps in the skin cells, affecting their adhesion and resulting in the characteristic blisters of the disorder. The condition is usually managed with treatments that focus on alleviating symptoms and preventing flare-ups, such as antibiotics for secondary infections, anti-inflammatory medications, and sometimes surgery.