Final answer:
Blood samples collected in EDTA, citrate, heparin, and sodium fluoride tubes are indeed acceptable for plasma extraction and analysis. These anticoagulants assist in preserving the samples for various tests. The specific anticoagulant and preparation methods depend on the analyte and analysis methods being used.
Step-by-step explanation:
The question asks whether blood samples in EDTA, citrate, heparin, and sodium fluoride tubes are acceptable for plasma extraction and analysis. This statement is generally true, as these additives are commonly used as anticoagulants to preserve blood samples for various analyses. The samples provided in these tubes can be centrifuged to obtain plasma, which is then further processed or analyzed depending on the requirements of the assay. Examples from the information given include samples quenched with methanol, plasma pretreated by solid-phase extraction (SPE), and plasma proteins not crossing the capillary cell membrane via facilitated diffusion.
Data collection indicates the use of different tubes for blood sample collection such as K2EDTA, heparin (lithium heparin or unspecified), and methods like liquid-liquid extraction and SPE followed by centrifugation to prepare the plasma for testing. These preparation steps are essential for the accurate measurement of different analytes, and the choice of anticoagulant may vary based on the specific test being performed.
It is important to note that the buffy coat consists of leukocytes and platelets, not proteins, and the collection and processing of other bodily fluids such as urine may require different preparation steps based on the analytes of interest.