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What are the aliphatic phenothiazines?

1) Chlorpromazine
2) Levomepromazine
3) Promazine
4) Triflupromazine

1 Answer

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Final answer:

Aliphatic phenothiazines like Chlorpromazine, Levomepromazine, Promazine, and Triflupromazine are part of the aromatic hydrocarbons within the tricyclic structure class, used predominantly for treating psychiatric illnesses and have additional antiemetic and antinausea properties.

Step-by-step explanation:

Aliphatic phenothiazines are a subclass of phenothiazines used primarily in the management of psychiatric illnesses like schizophrenia but also have properties like antiemetic, antinausea, and antihistaminic effects. The phenothiazines have a tricyclic structure which includes two benzene rings linked through a sulfur and a nitrogen atom. This chemical structure falls under the umbrella of aromatic hydrocarbons due to the presence of benzene rings, which differentiates them from aliphatic hydrocarbons that would be classified as an alkane, an alkene, or an alkyne based on the absence or presence and type of carbon-to-carbon bonds.

The specific examples you provided, 1) Chlorpromazine, 2) Levomepromazine, 3) Promazine, and 4) Triflupromazine, are all members of the phenothiazine family with varying substitutions that modify their efficacy and effects. For example, chlorpromazine is known not only for its psychiatric applications but also for its other clinically useful effects. The efficacy of phenothiazines is influenced by the substitution of electron-withdrawing groups at certain positions on the tricyclic core.

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