Final answer:
The nurse should include increased thirst and muscle weakness as manifestations of hypercalcemia when teaching about calcitonin-salmon. Weight gain and decreased urine output are not directly associated with hypercalcemia.
Step-by-step explanation:
When teaching a client who has a prescription for calcitonin-salmon for the treatment of hypercalcemia, the nurse should explain that this medication aids in normalizing high calcium levels in the blood, which have symptoms and manifestations. These manifestations, due to the overactivity of the parathyroid hormone or disorders such as malignancies leading to hypercalcemia, may include: increased thirst, muscle weakness, lethargy, sluggish reflexes, constipation, loss of appetite, and confusion. In severe cases, hypercalcemia can lead to a coma. Calcitonin-salmon works against these effects by promoting calcium deposition in bones and reducing the movement of calcium from bones to the bloodstream, effectively lowering the high calcium levels. Among the options provided, increased thirst (1) and muscle weakness (2) are direct manifestations of hypercalcemia that the nurse should include in the teaching. Weight gain (3) and decreased urine output (4) are not directly associated with hypercalcemia and thus should not be the main focus of the teaching related to calcitonin-salmon.