Final answer:
Precleaning and disinfecting the surface between patients is the best method to decontaminate a surface in a dental treatment area with difficult-to-clean features.
Step-by-step explanation:
The best method used to decontaminate a surface in a dental treatment area with crevices, knobs, or other difficult-to-clean features is to preclean and disinfect the surface between patients. This ensures that the surface is thoroughly cleaned and free from any potential contaminants. Using a surface barrier to prevent contamination and wiping the surface with alcohol may help to some extent, but they may not be as effective in removing all microbes and ensuring proper decontamination.