Final answer:
Pupillary response in pediatric patients may be abnormal in the presence of traumatic brain injury, opioid overdose, and migraine, but not in normal development. The answer is option 4.
Step-by-step explanation:
In pediatric patients, pupillary response may be abnormal in the presence of traumatic brain injury, opioid overdose, and migraine. However, it is not abnormal in the presence of normal development.
Pupillary response in pediatric patients may be abnormal in the presence of various medical conditions, but it is typically normal in the course of normal development. The pupils of infants and children can react to light and adjust appropriately as part of the normal physiological development.
Conditions such as traumatic brain injury, opioid overdose, and migraine can affect pupillary response. Traumatic brain injury may disrupt the normal functioning of the autonomic nervous system, opioids can cause miosis (constricted pupils), and migraines may be associated with changes in pupillary size and reactivity during an attack.