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Which pituitary adenoma requires neurosurgical evaluation?

1) Prolactinoma
2) Non-functioning adenoma
3) Cushing's disease
4) Acromegaly

User DineshNS
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Final answer:

Pituitary adenomas associated with acromegaly, indicated by the overproduction of GH, require neurosurgical evaluation due to the possibility of complications arising from the tumor's mass effect, such as vision problems and hormone regulation disruptions.

Step-by-step explanation:

A pituitary adenoma that requires neurosurgical evaluation is typically one associated with acromegaly, a condition caused by overproduction of Growth Hormone (GH) in adults. This excess GH is most often secreted by a tumor in the adenohypophysis, or the anterior pituitary gland, leading to characteristic features such as an abnormally enlarged skull, hands, fingers, and the thickening of soft tissues in various facial areas. The need for a neurosurgical evaluation is due to the potential complications that can arise from the mass effect of the tumor, such as compression of the optic chiasm leading to visual disturbances like tunnel vision, or other local structures within the brain.

The anterior pituitary gland's regulation of hormone production can be directly influenced by pituitary adenomas, consequently affecting target tissues for hormones such as prolactin. Negative feedback mechanisms, such as those involved in the function of the parathyroid gland to regulate calcium levels, can be disrupted in cases where tumors, including those on the pituitary gland, lead to over- or under-secretion of essential hormones.

User SteveLambert
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