Final answer:
Acamprosate is the pharmacologic agent that could help reduce the patient's alcohol consumption and increase abstinence.
Step-by-step explanation:
The pharmacologic agent that could help reduce the patient's alcohol consumption and increase abstinence is Acamprosate. Acamprosate is an FDA-approved medication for the treatment of alcohol dependence. It works by reducing cravings and restoring the balance of certain chemicals in the brain that have been disrupted by long-term alcohol use.
Unlike the other options listed (Amitriptyline, Paroxetine, Promethazine, and Venlafaxine), which are not specifically indicated for alcohol dependence, Acamprosate has been shown to be effective in reducing alcohol consumption and promoting abstinence.