Question

What is an absolute contraindication to the use of TPA/fibrinolytic therapy?

1) Recent major surgery or trauma within the past 2 weeks
2) Active internal bleeding
3) Known bleeding diathesis
4) All of the above

Answer 1

All the listed options (recent major surgery or trauma within the past 2 weeks, active internal bleeding, and known bleeding diathesis) are absolute contraindications to the use of TPA/fibrinolytic therapy.

Step-by-step explanation:

An absolute contraindication to the use of TPA/fibrinolytic therapy includes all of the following: 1) Recent major surgery or trauma within the past 2 weeks, 2) Active internal bleeding, and 3) Known bleeding diathesis. These conditions represent significant risks and using TPA, or other fibrinolytic agents could exacerbate bleeding and be life-threatening. It's imperative for healthcare providers to carefully evaluate a patient's medical history and current condition before administering thrombolytic therapy.