Final answer:
Inappropriate angiogenesis is linked with various pathologies including cancer, wherein tumors stimulate new blood vessel growth; achondroplasia, where bone growth irregularities might relate to vascular issues; and idiopathic juxtafoveal retinal telangiectasia, a disease with abnormal retinal vessels.
Step-by-step explanation:
Inappropriate angiogenesis, the process where new blood vessels form from pre-existing ones, can be associated with several medical pathologies. Here are three examples:
- Cancer: Tumors can stimulate the formation of new vessels in order to supply themselves with nutrients and oxygen. This process is targeted by drugs known as angiogenesis inhibitors in cancer treatment.
- Achondroplasia: This condition involves abnormal bone growth and can be associated with irregular blood vessel development.
- Idiopathic juxtafoveal retinal telangiectasia: This eye disease involves dilated and twisted retinal blood vessels, affecting vision.
Understanding the association of angiogenesis with these pathologies is important for developing targeted therapies, such as the EPR effect in cancer treatment, where abnormal tumor vasculature is exploited to deliver therapeutic agents.