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Name some conditions with defects in phagocytic function?

1) Leukemia
2) Diabetes
3) HIV/AIDS
4) All of the above

1 Answer

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Final answer:

Conditions with defects in phagocytic function include both inherited disorders like chronic granulomatous disease and severe combined immunodeficiency (SCID), as well as acquired conditions like HIV/AIDS. Leukemia and diabetes are not primarily associated with phagocytic defects but can lead to a weakened immune system.

Step-by-step explanation:

Conditions with defects in phagocytic function include certain inherited and acquired immunodeficiencies. Primary immunodeficiencies are genetic and often present at birth, like chronic granulomatous disease and severe combined immunodeficiency (SCID). Secondary immunodeficiencies are acquired later in life due to various factors like infections (e.g., HIV/AIDS which leads to AIDS), environmental exposures, or lifestyle.

Leukemia is not primarily known as a defect in phagocytic function but rather a cancer of the body's blood-forming tissues, including the bone marrow and lymphatic system. Diabetes is a metabolic disorder and does not directly cause a defect in phagocytic function. However, both conditions can lead to a weakened immune system.

Therefore, of the options provided, HIV/AIDS would be a correct answer as it causes a significant decrease in CD4 T cells due to various mechanisms, leading to a compromised immune system. Other conditions like agammaglobulinemia and chronic granulomatous disease are associated with primary immunodeficiencies affecting phagocytic function.

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