Final answer:
The targeted reversal agent for dabigatran (Pradaxa) is idarucizumab (Praxbind), which is used in cases such as major bleeding or urgent surgery to counteract the anticoagulant effects of dabigatran.
Step-by-step explanation:
The targeted reversal agent for dabigatran (Pradaxa) is idarucizumab (Praxbind). Dabigatran is a direct thrombin inhibitor, which is a type of anticoagulant used to prevent and treat blood clots. In cases where there is a need to reverse the anticoagulant effects of dabigatran, such as in the event of a major bleeding or an urgent surgery, idarucizumab is administered as it is specifically designed to neutralize the effects of dabigatran by binding to it directly and allowing normal clot formation.
Other anticoagulants, such as rivaroxaban (Xarelto), apixaban (Eliquis), and warfarin (Coumadin), each have their own specific reversal agents or strategies. Rivaroxaban and apixaban, which are Factor Xa inhibitors, can be reversed using andexanet alfa, while the effects of warfarin can be countered with vitamin K or prothrombin complex concentrates.