Final answer:
The question involves pharmacy practices in medicine, where a pharmacist must refuse to fill a prescription for pemoline that is significantly outdated, as controlled substance prescriptions have a limited validity period from the date of issuance.
Step-by-step explanation:
The subject of this question relates to the field of Medicine, more specifically to pharmacy practices. When a woman presents a prescription for pemoline that is dated several months prior, on March 3, but it is currently September 27, the pharmacist should refuse to fill the prescription. Prescriptions for controlled substances have a limited validity period from the date of issuance, and pemoline, being a stimulant with potential for abuse, falls under this category. Typically, the validity is no more than 6 months, depending on the state laws. Therefore, it is essential for the pharmacist to adhere to legal and professional standards when filling prescriptions.