Final answer:
The most important question to ask a male client during a digital rectal examination is about burning with urination or odor in urine.
Step-by-step explanation:
The most important question to ask a male client who is in for a digital rectal examination is: "Do you notice any burning with urination or any odor to the urine?" This is because these symptoms may indicate a urinary tract infection or other urinary issues that may be affecting the client's health.