Final answer:
The great saphenous vein is located medially in the leg and thigh, and it drains into the popliteal vein.
Step-by-step explanation:
The great saphenous vein is located on the medial surface of the leg and thigh. It collects blood from the superficial portions of these areas and drains into the popliteal vein. The popliteal vein then passes behind the knee and becomes the femoral vein.