Final answer:
Topical ophthalmic medications should be applied one after the other with a gap between applications, unless otherwise directed by a doctor.
Step-by-step explanation:
If the patient requires multiple topical ophthalmic medications in the same eye, these should be applied one after the other with a 5-10 minute gap between applications to ensure proper absorption and to prevent the second medication from washing out the first. This method of application is generally recommended unless otherwise instructed by a healthcare professional. It is essential to follow the doctor's instructions closely, as they may have specific guidance based on the types of medications and the patient's unique circumstances.