Final answer:
The kidneys and liver are commonly affected by drug toxicity, playing major roles in the body's detoxification processes. Impairment of these organs can result in the accumulation of toxins, leading to severe health issues and potentially affecting other systems such as the brain.
Step-by-step explanation:
Organs commonly affected by drug toxicity include the kidneys and liver. These organs are vital for detoxification processes and can be impacted severely by toxic substances. The liver functions to break down or modify toxic substances through a process called drug metabolism. However, this sometimes leads to toxication, especially if the metabolite is more toxic than its precursor.
The kidneys are crucial for removing waste products from the blood and maintaining overall homeostasis. Conditions that reduce kidney function can lead to a build-up of toxins, resulting in symptoms such as weakness, lethargy, and heart arrhythmias. Failures in the liver, such as severe impairment or exposure to certain toxic chemicals like carbon-tetrachloride, can lead to the accumulation of toxins in the bloodstream, which may eventually impair brain cells.
Both the liver and kidneys are involved in intricate detoxification mechanisms. When these organs fail or are functioning improperly due to drug toxicity, the repercussions extend throughout the entire body, affecting one’s well-being and survival.