Final answer:
Tramadol not only provides analgesia but also inhibits the reuptake of serotonin and norepinephrine, enhancing their effects in the nervous system.
Step-by-step explanation:
In addition to providing analgesia, tramadol has been shown to inhibit the reuptake of serotonin and norepinephrine. This action allows these neurotransmitters to remain active in the synaptic cleft for a longer duration, which can enhance their effectiveness. Tramadol is a unique analgesic as it combines opioid receptor agonism with the inhibition of serotonin and norepinephrine reuptake, characteristics that differentiate it from traditional opioids like morphine. While it does possess narcotic properties at higher doses, leading to potential drowsiness and loss of consciousness, it does not cause respiratory depression to the same extent as morphine. Additionally, tramadol is not notably associated with significant delay in gastric emptying or with the inhibition of cholinesterase.