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Which statement correctly relates the pressures found within the renal corpuscle:

A. the net filtration pressure (NFP) is lower than the blood colloid osmotic pressure (BCOP)
B. the net filtration pressure (NFP) is the difference between the blood colloid osmotic pressure (BCOP) and the net hydrostatic pressure (NHP)
C. blood colloid osmotic pressure (BCOP) and capsular hydrostatic pressure (CsHP) both offer resistance to the glomerular filtration pressure (GFP)
D. the capsular hydrostatic pressure (CsHP) is equal to the glomerular filtration pressure (GFP

User Managu
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Final answer:

The capsular hydrostatic pressure (CsHP) is not equal to the glomerular filtration pressure (GFP); instead, the net filtration pressure (NFP) is determined by the difference between the glomerular blood hydrostatic pressure and the sum of the CsHP and the blood colloid osmotic pressure, resulting in an NFP of about 10 mm Hg.

Step-by-step explanation:

Understanding Renal Corpuscle Pressures

The statement that the capsular hydrostatic pressure (CsHP) is equal to the glomerular filtration pressure (GFP) is incorrect. In the renal corpuscle, the filtration process is driven by the net filtration pressure (NFP), which is calculated as the difference between the glomerular blood hydrostatic pressure (GBHP) and the sum of the capsular hydrostatic pressure (CsHP) plus the blood colloid osmotic pressure (BCOP). Specifically, NFP is represented by the equation NFP = GBHP - [CsHP + BCOP] = 10 mm Hg. This equation illustrates that the actual driving force for filtration is the GBHP, which must exceed the sum of the CsHP and BCOP. The GBHP is typically around 55 mm Hg, the CsHP is approximately 15 mm Hg, and the BCOP due to plasma proteins is about 30 mm Hg. As a result, the actual NFP that facilitates glomerular filtration is approximately 10 mm Hg.

The kidneys utilize hydrostatic pressure to filter blood, creating urine as the filtrate. Hydrostatic pressure, which opposes osmotic pressure, is sufficient for this process due to the pressure gradient that exists across the filtration membrane. The autoregulatory mechanisms of the kidney ensure that there is a relatively steady flow and filtration rate despite substantial systemic pressure fluctuations.

User Joe Davison
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